This record is not really all-inclusive. Be sure to refer to straightforward drug information assets to look for particular interactions.
The dosage relies on your health-related ailment, age, and reaction to treatment. Giving the medication way too rapidly into a vein can cause critical side effects. If giving this medication into a vein, inject it little by little into a sizable vein. Don't inject this medication into an artery or in to the skin.
Distribution: Diazepam is highly lipophilic. Though You will find a moderately rapid onset of action, the drug rapidly redistributes. Diazepam and its metabolites have substantial plasma protein binding.
Seizures. Taking diazepam tablets with other medicines used to treat epilepsy can cause an increase in the selection or severity of grand mal seizures.
There's a probably suitable interaction concerning diazepam and compounds which inhibit selected hepatic enzymes (specially cytochrome P450 3A and 2C19).
A lower dose is usually recommended for people with Serious respiratory insufficiency, due to the risk of respiratory depression.
Call your healthcare provider between visits as required, especially If you're anxious about symptoms.
Before taking diazepam, notify your health care provider or pharmacist if you are allergic to it; or to other benzodiazepines (such as oxazepam, temazepam); or if you have any other allergies.
Valium’s longer elimination half-life implies that adverse effects may well last longer than Xanax or other benzodiazepines. This should be taken into effect when deciding on appropriate therapy.
Some possible businesses buy drug tests during the interviewing method to display for doable drug misuse. Or, a klonopin to valium conversion physician will want to make sure you don't have traces of Valium in your process before prescribing another medication.
Verywell Thoughts content articles are reviewed by board-Licensed physicians and mental healthcare professionals. Healthcare Reviewers verify the material is comprehensive and accurate, reflecting the latest evidence-primarily based analysis. Written content is reviewed before publication and upon substantial updates. Learn more.
Diazepam has a danger for abuse and addiction, which can cause overdose and death. Taking this medication with alcohol or other drugs that can cause drowsiness or respiration issues (especially opioid medications for instance codeine, hydrocodone) may possibly cause incredibly major side effects, including death. To lower your danger, your physician must have you take the smallest dose of diazepam that works, and take it to the shortest attainable time.
Metabolism: Diazepam is generally damaged down by the microsomal enzymes CYP2C19 and CYP3A4 enzymes to various active metabolites, generally desmethyldiazepam.
Diazepam is actually a Schedule IV controlled substance with the probable for abuse. Improvement of dependence and tolerance can happen in addiction-susceptible, long-term treatment or All those sufferers taking superior doses. Therefore, these people should be under watchful supervision; the moment somebody develops dependence, the potential risk of establishing withdrawal symptoms improves.